Lilly Targets Aduhelm With Aggressive Plans For Donanemab In Alzheimer’s

Lilly plans a head-to-head study of donanemab versus Biogen’s Aduhelm to see which clears amyloid plaque better and has begun a rolling BLA toward accelerated approval of the Alzheimer’s drug.

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Lilly has Biogen in its sights for Alzheimer's disease competition • Source: Alamy (hoch2wo / Alamy Stock Photo/Alamy Stock Photo)

Eli Lilly and Company placed a target on the back of recently approved and controversial Alzheimer’s drug Aduhelm (aducanumab) on 26 October, outlining plans during its third quarter earnings call to run a Phase III head-to-head clinical trial testing the company’s donanemab against Biogen, Inc./Eisai Co., Ltd.’s drug to see which antibody does a better job of clearing amyloid from the brain.

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