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After ‘Puzzling’ Results For Antibody Drug, AC Immune’s Alzheimer’s Vaccine Shows Early Promise

A Blip Or A Breakthrough In Tau?

 
• By Andrew McConaghie

Another hard-to-explain result in Alzheimer’s, with AC Immune claiming the first ever validation of anti-tau therapy, but others are more circumspect.

AC Immune
AC Immune has Alzheimers's collaborations in anti-tau and beta-amyloid modalities with companies such as Lilly, J&J and Roche. • Source: Alamy

Swiss biotech AC Immune has presented data from two of its lead candidates targeting the tau protein’s role in Alzheimer’s disease, including what it claims is the first study to show efficacy against cognitive decline.

But as is so often seen in the field, the data are far from straightforward, and many outside

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