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New Player Joins Search For Effective Huntington's Therapies

LoQus23 Looks To Tackle Neurodegenerative Disease

 
• By Kevin Grogan

Despite recent setbacks for Roche and Wave's respective antisense offerings, both those two firms and a number of other companies are trying a variety of approaches to find a treatment for Huntington's.

Confused undecided businessman watches the complicated road
Huntington's drug development difficult to navigate • Source: Archive

Hopes of a breakthrough in Huntington’s disease have been dashed a number of times, not least this year, but the emergence from stealth mode of a UK biotech backed by Novartis AG's venture arm could provide some optimism down the line for patients with the fatal, inherited neurodegenerative disorder.

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• By Dexter Jie Yan

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Camzyos nHCM Failure Could Open Door To Threat From Cytokinetics’ Aficamten

 
• By Alaric DeArment

BMS’s Phase III ODYSSEY-HCM study did not show statistical significance for either of its two primary endpoints.

More from R&D

Henlius In David Versus Goliath Race With Pfizer For First PD-L1 ADC

 
• By Dexter Jie Yan

While Henlius Biotech’s PD-L1-targeting antibody-drug conjugate HLX43 is struggling to catch up with Pfizer’s PF-08046054, the global frontrunner in the space, a key differentiation of the China-originated asset could lie in PD-L1-negative patients.

AstraZeneca Logs Japan Growth Despite Price Cuts

 
• By Lisa Takagi

AstraZeneca logs growth in Japan despite a big reimbursement price cut for one of its top sellers and expects 40 approvals in the country over the next six years.

Camzyos nHCM Failure Could Open Door To Threat From Cytokinetics’ Aficamten

 
• By Alaric DeArment

BMS’s Phase III ODYSSEY-HCM study did not show statistical significance for either of its two primary endpoints.