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Xian Under Lockdown, mRNA Vaccines Remain Elusive In China

Domestic Shot May Need Two Boosters Vs Omicron

 
• By Brian Yang

A relatively large outbreak in another major Chinese city after original epicenter Wuhan heightens the urgency for a more effective mRNA vaccine.

XIAN A VIBRANT CITY IN CHINA ENCOUNTERS STRICT LOCKDOWN AFTER WUHAN IN JAN 2020
XIAN IN SEPTEMBER 2021 BEFORE THE STRICTEST LOCKDOWN AFTER WUHAN IN JANUARY 2020 • Source: Brian Yang/Scrip

Xi'an, a city of 13 million people in Northeastern China, is under strict lockdown amid a regional COVID-19 outbreak, the worst in the country since January 2020 when similarly-sized Wuhan was placed under drastic restrictive measures.

Most immediately, the move has hit hard those in the city seeking healthcare and medical emergency services. In one publicized...

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Chinese Biotech VC/PE Fundings Rise But Still Modest

 
• By Dexter Jie Yan

LTZ Therapeutics and Beijing Sungen Biomedical are among the Chinese biotechs raising new funding, of around $40m each, based on their clinical assets with novel mechanisms of action. While fundings have risen, they remain moderate however.

Degron Eyes Deals For Novel Molecular Glue Degrader Assets

 
• By Dexter Jie Yan

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Ascentage Broadens Horizons As Pipeline Shows Renewed Promise

 
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Ascentage will share at ASCO new clinical data on its Bcl-2 inhibitor lisaftoclax, part of the Chinese firm's novel pipeline, on which its CEO shared with Scrip plans and strategy, along with some views on the use of RWD in China.

Strong Data For CARsgen’s CAR-T In Late-Line Gastric Cancer

 
• By Dexter Jie Yan

In first confirmatory randomized controlled trial of any CAR-T therapy in solid tumors, CARsgen’s Claudin 18.2-targeting satri-cel reduced risk of death or disease progression by 63% in Chinese patients with gastric/gastroesophageal junction cancer.

More from Focus On Asia

MetaVia Sees Obesity Opportunities Despite Challenging US Market

 
• By Jung Won Shin

Despite new challenges related to obesity drug insurance coverage in the US, MetaVia's CEO is confident in the company's novel contender, which unlike rival GLP-1 therapies doesn’t require dose titration.

Public Health And Innovation: Addressing Gaps, Pharma’s Role

 
• By Anju Ghangurde

Expert panel including Ashok Venkitaraman, director of the Cancer Science Institute of Singapore, discusses public health challenges and innovations to help address these. Long-acting drugs, intercepting cancer early and “design thinking” by ophthalmologists in India were among the talking points.

Loss Of Exclusivity Product Launches To Fuel Aurobindo’s FY26 Europe Growth

 
• By Vibha Ravi

Aurobindo is banking on launches of loss of exclusivity products and biosimilars to fuel sales in Europe as it awaits a US announcement on tariffs and predicts high single-digit growth overall during FY26 for now