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Sierra Sees Momelotinib ‘Sweet Spot’ In Anemic Myelofibrosis Population

 
• By Alaric DeArment

Sierra announced Phase III results for the JAK inhibitor in anemic myelofibrosis patients with previous JAK exposure, a difficult-to-treat population. Trial investigator Ruben Mesa talked to Scrip about some of the advantages.

3-D Rendering Red Blood Cells
Sierra announced data from the Phase III MOMENTUM study of momelotinib in myelofibrosis • Source: Shutterstock

Sierra Oncology, Inc. is hoping to take a sizable chunk of the market for myelofibrosis (MF) with Phase III data showing positive results for its JAK inhibitor momelotinib in patients who previously received JAK inhibitor treatment, a setting that has few therapy options. Still, how physicians use it and other JAK inhibitors may boil down to patient phenotype.

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