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Silence Therapeutics Could Rival Amgen And Novartis With siRNA Therapy

Early Results Attract Big Pharma Interest

 
• By Andrew McConaghie

The UK biotech could have a major gene silencing drug on its hands but will need a big pharma partner to help it realize the candidate’s potential.

Cardiovascular
SLN360 is one of a wave of new RNA-based therapies targeting lipoprotein(a) (Lp(a) . • Source: Alamy

Silence Therapeutics looks to be in a strong position to compete among a wave of RNA-based therapies targeting lipoprotein(a) (Lp(a) and may even emerge with a best-in-class molecule that is already generating interest from potential big pharma partners.

That interest around its short interfering ribonucleic acid (siRNA) therapy SLN360 revved up considerably after the small UK biotech released

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