Scynexis, Inc. is poised to add a valuable second indication to labeling for its novel, first-in-class antifungal Brexafemme, announcing on 10 February that the oral triterpenoid met the primary endpoint in a 260-patient Phase III study in recurrent vaginal yeast infections, also known as vulvovaginal candidiasis. The company intends to submit a supplemental new drug application for rVVC during the first half of 2022, CEO Marco Taglietti told a same-day investor call.
Scynexis Data Show Brexafemme Prevents VVC Recurrence
Phase III data showed that the first-in-class oral antifungal can prevent recurrence of vaginal yeast infections, a potentially valuable label addition to the current indication for acute treatment.
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