The top biopharma companies are spending more on R&D than they did 10 years ago as a percentage of sales but even with investment, R&D productivity will not offset a looming patent cliff that begins in 2023 when AbbVie Inc. will lose US exclusivity for Humira (adalimumab) and peaks in the 2025/2026 time period, according to a report from the consulting firm EY.
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