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Ocuphire Posts Second Phase III Success In Reversing Pupil Dilation

 
• By Joseph Haas

Nyxol is almost set for an NDA filing for reversal of dilation during eye exams/surgery. The reformulation of phentolamine is also being studied in presbyopia, setting up possible competition with AbbVie’s Vuity.

Eye exam
Ocuphire hopes Nyxol will prove a popular option with eye exam patients • Source: Alamy

Ocuphire Pharma, Inc. reported statistical significance for its eye drop candidate Nyxol in a second pivotal Phase III study in reversal of pharmacologically induced mydriasis (or pupil dilation). Management told investors on a 29 March call that the company anticipates filing the candidate for approval at the US Food and Drug Administration later this year.

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