Adagio Therapeutics, Inc. plans to seek an emergency use authorization (EUA) for the monoclonal antibody ADG20 (adintrevimab) for COVID-19 as Phase II/III data have shown it effective at preventing and treating the disease even as the Omicron variant has become prevalent, despite earlier data indicating significantly reduced efficacy against the variant. But its efficacy against a newer, rapidly growing subvariant of Omicron remains uncertain.
Can Adagio’s Adintrevimab Hold Up Against Omicron BA.2?
The company will seek an EUA for the COVID-19 antibody after trial data indicated efficacy against Omicron, but studies have called into question its potency against the rapidly expanding subvariant.
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