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Cytokinetics Rocked By Another Omecamtiv Setback

But Hope Remains For Subpopulation

 
• By Ayisha Sharma

The biotech’s cardiology asset has failed an advanced study focused on exercise capacity in heart failure, having underwhelmed observers with past data, but hope remains that the LVEF subset could be a saving grace.  

The white heart pills on a colored background. The concept of a healthy life. Heart disease. Arrhythmia, heart failure. Health problem.
More Than Two Million People In The US Have Severe Heart Failure • Source: Alamy

Cytokinetics, Inc.’s omecamtiv mecarbil has disappointed in yet another Phase III study of heart failure with reduced ejection fraction (HFrEF), but the firm is holding on to the hope that it could still benefit a specific patient subpopulation.

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