The Next Big Patent Cliff Is Coming, And Time Is Running Out To Pad The Fall

Blockbusters like Stelara, Eliquis, Prolia and Ibrance are poised to lose US exclusivity over the next five years; pressure is mounting for industry to replenish the portfolio with the next high-growth brands.

The pharmaceutical industry is in the midst of a steady period of moderate growth, but financial pressure will build toward the middle part of the decade as many key blockbuster brands face loss of exclusivity (LOE). The window for launching new growth drivers to fill the expected revenue gap is narrowing.

Investors are growing wary about the period from 2025-2030, when many big brands will lose market exclusivity in the US...

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