Already a big seller, Boehringer Ingelheim GmbH's Jardiance looks set to become a mega-blockbuster as the diabetes drug's expansion into heart failure, and very probably kidney disease, brings in millions more patients and millions more euros.
Sales of Jardiance (empagliflozin) in 2021 were boosted by significant label expansions which made the SGLT2 inhibitor, initially approved in 2014 for diabetes, the first drug in the class to be given the green light for heart failure with both reduced ejection fraction (HFrEF) and preserved left ventricular ejection fraction (HFpEF). The Eli Lilly and Company-partnered drug contributed €3.9bn (+28.6%) to BI's coffers and the heart failure approvals will add a considerable amount to that total
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