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Bad Omen Or Opportunity? Roche’s TIGIT Failure Hits Rivals Hard

Arcus/Gilead Readout Expected Next

 
• By Andrew McConaghie

After two failures in a row from Roche, the TIGIT hypothesis is looking shaky, but it is too early to write off the class yet.

Roche_HQ
Roche has a lot riding on its SKYSCRAPER studies - and still hopes they will yield benefits for patients. • Source: Roche

The failure of Roche’s frontrunner TIGIT immunotherapy tiragolumab in a second Phase III trial has not only dragged down the Swiss pharma’s prospects, but also the share price of its biotech rivals.

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