Sanofi Closes In On A Pair Of Approval Firsts

Dupixent Approvals Expanded As Xenpozyme Gets CHMP Nod

The French major has secured a fourth approval, in eosinophilic esophagitis, for Dupixent, while the EMA is set to make Sanofi's enzyme replacement therapy, Xenpozyme, the first drug approved in Europe for acid sphingomyelinase deficiency.

Sanofi
• Source: Sanofi

Sanofi is celebrating a pair of regulatory successes for drugs that will be the first treatments to be approved for two rare diseases, acid sphingomyelinase deficiency (ASMD) and eosinophilic esophagitis (EoE).

First up is another approval in the US for the mega-blockbuster Dupixent (dupilumab) which has just received the green light from the Food and Drug Administration for EoE, a chronic disease driven by type 2 inflammation that damages the esophagus and prevents it from working properly, making swallowing a painful and worrisome choking experience

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