Etrasimod Results Justify Pfizer’s Leap Of Faith In Arena Buyout

Big Pharma Executed $6.7bn Deal Without Seeing Phase III Data

Detailed data presented at Digestive Disease Week show competitive efficacy in ulcerative colitis and a potential best-in-class safety profile for the S1P receptor modulator Pfizer acquired earlier this year. 

Businessman taking a leap of faith
Pfizer saw only Phase II data and blinded Phase III results for etrasimod ahead of its Arena buyout • Source: Shutterstock

Based on an incomplete data set and its own understanding of the ulcerative colitis (UC) market, Pfizer Inc. took a bit of a leap of faith in December when it agreed to acquire Arena Pharmaceuticals, Inc. for $6.7bn. But now detailed results from the Phase III ELEVATE UC clinical trials presented at Digestive Disease Week (DDW) on 24 May show that Pfizer’s M&A leap was not a misstep.

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