Praxis Precision Medicines, Inc. revealed a surprising Phase II/III failure for major depression disorder (MDD) candidate PRAX-114 but was praised by analysts for moving quickly to re-center its R&D efforts on mid-stage essential tremor and epilepsy programs.
Praxis Moves Away From Depression With Surprising Phase II/III Failure
With GABA-A modulator PRAX-114 missing all endpoints in a monotherapy study, Praxis will cease development of that drug and focus on its candidates for essential tremor and epilepsy.
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Aldeyra’s dry eye candidate reproxalap received a second FDA complete response letter, but the firm expressed confidence about refiling quickly based on two ongoing studies.
Pipeline Watch is a weekly snapshot of selected late-stage clinical trial events and approvals announced by pharmaceutical and biotech companies at medical and industry conferences, in financial and company presentations, and in company releases and statements.
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