ContraFect’s Path Forward Gets Murky With Exebacase Trial Failure

The company said it would discontinue the Phase III trial of the MRSA drug for futility, leaving it with no major catalysts and an uncertain cash position.

ContraFect said it stopped its Phase III trial of exebacase in MRSA for futility • Source: Shutterstock

While ContraFect Corporation.’s exebacase may still have a viable clinical development pathway, the company has found its overall clinical development program knocked back several places after a decision to stop its lead clinical trial, for methicillin-resistant Staphylococcus aureus (MRSA), for futility.

The company said 13 July that it would discontinue the Phase III DISRUPT trial of exebacase for futility based on...

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