Sesen Bio, Inc. is selling off a portfolio of anti-interleukin-6 (IL-6) antibodies to collaborator Roche Holding AG and looking to find a partner for its lead oncology asset, Vicineum, which was the subject of a complete response letter in 2021, with an eye toward saving money as the company maps out a new strategy following a meeting with the US Food and Drug Administration.
Sesen said on 18 July that it would pause further development of Vicineum (oportuzumab monatox) in the US after what it called a “thorough reassessment” that included the timeline and cost for an additional Phase III trial of the drug in non-muscle invasive bladder cancer (NMIBC) following recent discussions with the FDA