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Regulus Hit As Partner Sanofi Pulls Plug On Kidney Drug Study

Rare Kidney Diseases Proving Difficult For Both Companies

 
• By Andrew McConaghie

Sanofi has abandoned its study of lademirsen in Alport disease, but has not given up on the drug just yet as another indication remains in play.

Sanofi
Sanofi is to halt development against Alport syndrome, but will consider other potential targets. • Source: Shutterstock

Sanofi has decided to abandon development of Regulus Therapeutics’s lademirsen against a rare kidney disease after it failed to show benefit in an interim analysis.

The San Diego-based biotech disclosed in a regulatory filing that Sanofi was ending development of lademirsen (RG-012) for use against...

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