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VistaGen Staggered By Latest Clinical Setback, This Time In Social Anxiety

 
• By Joseph Haas

Failure of pherine nasal spray candidate in first of two Phase III trials for social anxiety disorder puts program in doubt, while the California biotech’s share price craters.

Public speaking anxiety
VistaGen tested its SAD candidate in a public speaking model • Source: Shutterstock

VistaGen Therapeutics, Inc. has rebounded from clinical development setbacks before, but investors imposed a severe penalty on the South San Francisco biotech on 22 July following its pre-market announcement that social anxiety disorder candidate PH94B failed to meet the primary endpoint in the first of two pivotal Phase III trials.

Trading at only $1.07 per share at the beginning of the day on 22 July – despite a clinical pipeline...

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• By Andrew McConaghie

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Another Day Another Win For Novartis’s Ianalumab – This Time In ITP

 
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IO Biotech Plans Cylembio Filing Despite ‘Narrowly Missed’ Phase III Endpoint

 
• By Mandy Jackson

The company plans to meet with the US FDA prior to submitting a BLA before the end of 2025 for its cancer vaccine as a first-line advanced melanoma treatment in combination with Keytruda.

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IO Biotech Plans Cylembio Filing Despite ‘Narrowly Missed’ Phase III Endpoint

 
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Sjögren’s Success For Ianalumab Shores Up Novartis’s Pipeline-In-A-Product Plans

 
• By Alexandra Shimmings

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Pipeline Watch: Five Approvals And Two Phase III Readouts

Pipeline Watch is a weekly snapshot of selected late-stage clinical trial events and approvals announced by pharmaceutical and biotech companies at medical and industry conferences, in financial and company presentations, and in company releases and statements.