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Newly Launched Replay Has Big Plans For Writing and Delivering ‘Big DNA’

Viral Vector Has 30 Times Capacity Of AAV

 
• By Andrew McConaghie

With a hub-and-spoke model, Replay has ambitious plans to solve multiple problems in genetic medicine and to disrupt the current AAV gene therapy model.

Herpes Simplex
One of the company's key technologies is a herpes simplex virus based gene therapy. • Source: Shutterstock

Replay, an ambitious new biotech start-up which aims to reprogram biology by writing and delivering ‘big DNA’, has been launched with $55m in seed financing.

Based in London and San Francisco, the company has assembled a portfolio of technologies that it says could help solve key challenges holding back genetic medicine, a strategy which it

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