Pfizer's Prevnar 20 Edges Closer To Infant Market, But Phase III Raises Some Questions

The pediatric market represents 70%-75% of the market for pneumococcal vaccines; Merck & Co.'s Vaxneuvance was already approved for infants earlier this year.

babies
Pfizer hopes to get Prevnar 20 approved for infants • Source: Shutterstock

Pfizer Inc. is aiming to bring its next-generation pneumococcal vaccine Prevnar 20 into the pediatric market – the larger market opportunity versus adults – so that it can be used in the same patients as the company's blockbuster Prevnar 13 and Merck & Co., Inc.'s newer 15-valent conjugate vaccine Vaxneuvance.

A Phase III clinical trial comparing the immunogenicity of the 20-valent pneumococcal conjugate vaccine candidate (20vPnC) to Prevnar 13 in infants at 2, 4, 6 and 12-15 months of age met the primary endpoint after four doses for all 20 serotypes, but

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