Future For Spexis Looks Far From Secure

Swiss Biotech Launched End of 2021

Spexis is hoping to get ColiFin, a therapy for chronic lung infections in cystic fibrosis patients, onto the US market but cannot start the necessary late-stage program without an injection of cash.

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Like many biotechs, Spexis is strapped for cash • Source: Shutterstock

Spexis AG, the Swiss biotech that was only created at the end of last year through the merger of troubled Polyphor AG and EnBiotix, is already facing an uncertain future as it battles for funds to survive.

The company began life on 31 December after Polyphor, struggling after the failure of its lead cancer asset balixafortide in a late-stage trial for breast cancer, was handed a lifeline by a link-up with EnBiotix, a US-based rare disease company focused on cystic fibrosis (CF). When Spexis launched, CEO Jeffrey Wager said the firm was looking forward to "advancing an innovative R&D pipeline and to engaging in unique strategic corporate development to create long-term shareholder value

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