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Merck KGaA Overcomes Ukraine Disruption To Keep MS Frontrunner On Track

FDA Has Approved Trial Adaptations

 
• By Andrew McConaghie

The German group is optimistic evobrutinib can be a blockbuster in multiple sclerosis and has adapted its pivotal trial to cope with disruption caused by the war in Ukraine.

Merck KGaA Darmstadt
Evobrutinib is one of two Phase III assets which Merck KGaA believes can achieve $1bn plus annual revenues • Source: Shutterstock

Merck KGaA is still on track to produce Phase III results from its multiple sclerosis drug evobrutinib in late 2023, which would keep it ahead of a crowded field of Bruton’s tyrosine kinase (BTK) inhibitor pipeline competitors.

The drug is also the most advanced candidate in its pipeline and carries with it the hopes of the German company’s near-term growth ambitions

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