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AstraZeneca Cancer Pipeline Boost With AKT And SERD Successes

A Pair Of ‘Wild Card’ Studies Pay Off

 
• By Alexandra Shimmings

A couple of trials for two investigational late-stage breast cancer candidates from AstraZeneca have each produced encouraging data for a novel drug class where rivals have previously hit clinical buffers.    

Doctor with Mammography - Image
• Source: Shutterstock

AstraZeneca PLC has produced positive topline breast cancer data for two of its novel pipeline candidates – the AKT inhibitor capivasertib and the next-generation SERD camizestrant – with both anticancer candidates succeeding where others have failed.

Topline data from the Phase III CAPItello-291 trial showed that capivasertib in combination with AstraZeneca’s older injectable SERD Faslodex (fulvestrant)...

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