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GSK’s Blenrep Hit By Trial Failure, Raising Questions About Its Future In The Myeloma Market

Phase III Study Misses Endpoint

 
• By Andrew McConaghie

The DREAMM-3 study was meant to be a confirmatory study for Blenrep, and its failure raises concerns over its use in earlier lines of therapy and the possibility that it could be removed from the market.

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DREAMM-3's failure does not bode well for further readouts in earlier myeloma therapy, and could even see Blenrep removed from the market. • Source: GSK

GSK’s efforts to build a presence in the multiple myeloma market with Blenrep (belantamab mafodotin) have suffered a major setback, after it failed to improve on standard second-line therapy in a confirmatory Phase III study.

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Pipeline Watch is a weekly snapshot of selected late-stage clinical trial events and approvals announced by pharmaceutical and biotech companies at medical and industry conferences, in financial and company presentations, and in company releases and statements.