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Bayer Goes All In With Asundexian And Pulls Two Other Factor XIa Projects

Potential Xarelto Successor Prioritized

 
• By Kevin Grogan

Despite promising mid-stage data for the Ionis-partnered fesomersen and osocimab, licensed from Aronora, the German major has plumped for asundexian as the priority compound for its Factor XIa efforts.

Bayer aerial
• Source: Bayer

Bayer AG has confirmed that of the three projects in its Factor XIa program, the full focus is now on the oral treatment asundexian, ahead of two partnered therapies – fesomersen and osocimab – which had also shown potential in mid-stage trials.

Asundexian is positioned as the next-generation Xarelto (rivaroxaban), the firm's blockbuster Factor Xa blood thinner, and Bayer CEO Werner Baumann...

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