Al Sandrock On His First Mission At Voyager: Cracking The Tau Alzheimer’s Puzzle

Ex-Biogen Research Head Prioritizes Anti-Tau Antibody

Interview: Twelve months on from exiting Biogen, Al Sandrock is once again leading innovation in neuroscience, and hopes to crack the tau nut in Alzheimer’s and prove that Voyager’s next-generation gene therapy system will be a breakthrough.

PET imaging
A PET image of the brain: Voyager believes its gene therapy can cross the blood brain barrier more effectively than existing capsids. • Source: Shutterstock

Al Sandrock left Biogen under a cloud last year, his 23 years in R&D leadership at the company ending abruptly amid growing controversy around its Alzheimer’s therapy Aduhelm (aducanumab). 

It was a disappointing end to his time at the company, where he had developed some of the most important neuroscience drugs of recent decades, such as the multiple sclerosis treatment Tecfidera (dimethyl fumarate) the rare disease antisense therapy

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