New IO Progress For Korea's NeoImmuneTech, GI Innovation

Mono, Combo Promise For Novel Assets

While Chinese bioventures continue to surge ahead in immuno-oncology R&D, NeoImmuneTech says its long-acting human IL-7 in combination with pembrolizumab shows Phase IIa clinical efficacy in gastrointestinal tumors. Another Korean firm, GI Innovation, says its bispecific fusion protein/pembrolizumab combo shows synergistic effects in solid tumors at Phase I/II.

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NeoImmuneTech, GI Innovation Unveil 'Encouraging' Early Data In Solid Tumors • Source: Shutterstock

NeoImmuneTech, Inc. and GI Innovation, both bioventures trading on South Korea’s Kosdaq market, have unveiled preliminary clinical data for their respective novel cancer immunotherapies either in combination with pembrolizumab or as monotherapy, which showed early promise in solid tumors. Both sets of results were presented at the recent Society for Immunotherapy of Cancer (SITC) 2022 annual meeting in Boston.

NeoImmuneTech, a US-based affiliate of Korean firm Genexine Inc., said efineptakin alfa (NT-I7), the only clinical-stage, long-acting human interleukin-7 therapy, showed clinical efficacy with pembrolizumab (Merck & Co., Inc.'s Keytruda) in relapsed/refractory gastrointestinal tumors

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