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Novartis’ Kisqali Could Challenge Pfizer’s Ibrance After Phase II First-Line Aggressive Breast Cancer Success

 
• By Ayisha Sharma

The Swiss major’s CDK4/6 inhibitor has met the primary endpoint in a Phase II trial in first-line aggressive advanced breast cancer, supporting off-label use as the firm goes head to head with Pfizer’s rival drug Ibrance.  

Image of blue woman with red circle in breast, representing breast cancer
Chemotherapy Remains The Treatment Of Choice When There Is Organ Damage • Source: Shutterstock

Novartis AG’ Kisqali has met the primary endpoint in a Phase II trial in first-line use in aggressive metastatic breast cancer trial which could boost off-label use in this setting as the Swiss major challenges rival Pfizer Inc.’s Ibrance in a highly anticipated pivotal trial.

RIGHT Choice set the CDK4/6 inhibitor Kisqali (ribociclib) plus endocrine therapy (ET) against combination chemotherapy in 222 pre- and peri-menopausal...

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