CAR-Ts May Be Closer Competitors To Lilly’s Jaypirca Than Fellow BTK Inhibitors

The Loxo@Lilly drug got FDA accelerated approval in mantle cell lymphoma as the first non-covalent BTK inhibitor, enabling its use in post-BTKi disease.

FDA Approved
Lilly's Loxo announced the FDA accelerated approval of Jaypirca • Source: Shutterstock

Eli Lilly and Company's newly approved, Jaypirca (pirtobrutinib), may have the same target as BTK inhibitors already on the market, but it belongs to a different class in terms of how it will fit into the mantle cell lymphoma (MCL) treatment paradigm, and that is key to the company's commercial strategy around the drug.

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