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Certa Plans Pivotal Scleroderma Trial As GPCR Antagonist Hits Phase II Bullseye

Australian Firm Has High Hopes

 
• By Ayisha Sharma

Certa’s lead candidate has shown promise in a mid-stage trial for the rare but debilitating skin disorder, triggering pivotal development plans to address the high unmet need.  

Plain sand on left with cracked sand on right, concept of dryness, skin
Scleroderma Causes Hardened, Thickened Skin And Muscle Weakness • Source: Shutterstock

Certa Therapeutics’ lead candidate, FT011, has hit the mark in a Phase II scleroderma trial, sparking Phase III plans as the firm edges closer to validating its approach of targeting an undrugged receptor in the inflammatory pathway.

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Pipeline Watch: Eight Approvals And Three Phase III Readouts

Pipeline Watch is a weekly snapshot of selected late-stage clinical trial events and approvals announced by pharmaceutical and biotech companies at medical and industry conferences, in financial and company presentations, and in company releases and statements.