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Roche’s Vabysmo Advantage Over Eylea Hard To See In Latest Head-To-Head

Both Drugs Dosed Monthly

 
• By Andrew McConaghie

Roche’s next-generation eye drug Vabysmo has enjoyed a strong launch, but new head-to-head trials in a potential new indication, retinal vein occlusion, appear to offers up few advantages over market leader Eylea.

Eye Test
Roche is aiming to add to Vabysmo's existing approvals in wet age-related macular degeneration and diabetic macular edema (DME). • Source: Shutterstock

Roche is looking compete against Regeneron/Bayer’s market-dominating blockbuster eye drug, Eylea, with its new challenger, Vabysmo, but newly unveiled Phase III head-to-head data in a potential third indication appear to show limited advantages over the older product.

Vabysmo (faricimab) offers the convenience of dosing intervals up to four months (after an initial run-in) versus every two months with Eylea (aflibercept) and gained its first US approval in wet age-related macular degeneration (AMD) and diabetic macular edema (DME) a year ago

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