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Exelixis’ Cabometyx R&D On Track Despite Pivotal Kidney Cancer Setback

 
• By Ayisha Sharma

The US firm’s Cabometyx has missed the mark in combination with Roche’s Tecentriq in a challenging kidney cancer setting, but analysts argue the setback is minimal as they highlight two major readouts coming this year.    

Blue and purple graphic image of pair of kidneys
There Could Be 15,000 Deaths Due To Kidney Cancer This Year • Source: Shutterstock

A regimen of Exelixis, Inc.’ Cabometyx and Roche Holding AG’s Tecentriq has missed the mark in the Phase III CONTACT-03 trial in advanced renal cancer patients, but is shrugging off the failure in light of more commercially important pivotal cancer readouts for the product expected later this year.

CONTACT-03 enrolled 522 people with locally advanced or metastatic clear cell or non-clear cell renal cell carcinoma (RCC) whose disease...

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