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Affibody And UCB Eye Humira’s Weak Spot In Hidradenitis Suppurativa

Following Positive R&D Milestones

 
• By Ayisha Sharma

The rival firms are advancing separate biologic candidates that target IL-17 in a bid to treat the more than 60% of hidradenitis suppurativa patients who remain uncontrolled on AbbVie’s Humira, with recent trial readouts showing promise.  

New Biologic Candidates For HS Could Challenge AbbVie's Humira • Source: Shutterstock

Pipeline candidates targeting IL-17 from Affibody AB/Acelyrin, Inc. and UCB S.A. have had positive mid- to late-stage readouts in hidradenitis suppurativa (HS), a debilitating skin condition that presents a high unmet need despite the availability of AbbVie Inc.’s anti-TNF blockbuster Humira.

HS is a chronic skin condition characterized by scarring, abscesses, malodor and pain

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