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Path Ahead For Neuraly’s NLY01 Unclear After Phase II Parkinson’s Disappointment

 
• By Ayisha Sharma

The US firm’s lead program has flunked a mid-stage trial in early Parkinson’s disease and, despite a promising efficacy signal in a younger patient cohort, its future remains uncertain.  

Shaking hand holding a cup, symptom of Parkinson's disease
Dyskinesia is a common symptom of Parkinson's disease • Source: Shutterstock

Neuraly, Inc.’s lead candidate, NLY01, has failed a Phase II trial in early Parkinson’s disease (PD) and while the firm touted a positive signal in under 60s, next steps for the program are unclear in the increasingly challenging indication.

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