Novo Nordisk Teams With Aspect Biosystems On Diabetes Cell Therapy

Aspect says its bioprinted tissue therapeutics include immune-resistant encapsulation, which Novo Nordisk hopes will offer a safer approach to type 1 diabetes cell therapy.

3D printer
Novo Nordisk/Aspect alliance with apply 3D printing to cell therapy • Source: Shutterstock

In a deal that Aspect Biosystems Ltd. CEO Tamer Mohamed suggested could mean science fiction coming to real life, the Vancouver, BC-based firm focused on bioprinted tissue therapeutics is teaming with Novo Nordisk A/S to develop allogeneic cell therapies for type 1 diabetes. The companies unveiled their partnership on 12 April, with Aspect getting $75m up front plus up to $650m in earnouts tied to as many as four programs.

A leader in the diabetes space, Novo Nordisk has been working on stem-cell-derived islet cell therapies for type 1 diabetes for years and told Scrip it sees Aspect’s technology, which offers immune-resistant encapsulation for cell therapies, as potentially a safe way to deliver such therapies to patients. Spun out from technology developed at the University of British Columbia, Aspect inked a partnership with Johnson & Johnson affiliate DePuy Synthes in 2017 to develop a bioprinted tissue device for surgical knee meniscus replacement

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