AstraZeneca’s Imfinzi Scores Neoadjuvant/Adjuvant NSCLC Two-fer At AACR

The PD-L1 inhibitor showed efficacy in the neoadjuvant/adjuvant setting, where Merck is developing Keytruda as well. BMS’s Opdivo was the first to win approval in neoadjuvant NSCLC.

Lung Cancer — AstraZeneca announced data for Imfinzi in neoadjuvant/adjuvant non-small cell lung cancer at AACR • Source: Shutterstock

AstraZeneca plc’s PD-L1 inhibitor Imfinzi (durvalumab) is one step closer to becoming a therapy both for neoadjuvant and adjuvant treatment of non-small cell lung cancer (NSCLC) with new data from the Phase III AEGEAN study at the American Association for Cancer Research annual meeting.

The positive results potentially sets it up as a competitor to Bristol Myers Squibb Company’s PD-1 inhibitor Opdivo (nivolumab),...