Bluebird Files Sickle Cell Gene Therapy, Just Weeks Behind Vertex

The company is seeking a priority review from the US Food and Drug Administration.

horse race
A race is on in gene therapy for sickle cell disease • Source: Shutterstock

bluebird bio remains in a tight race with Vertex Pharmaceuticals Incorporated to bring the first gene-altering therapy to market for sickle cell disease, announcing on 24 April that it has filed a biologics license application (BLA) with the US Food and Drug Administration for the gene therapy lovotibeglogene autotemcel (lovo-cel) in patients with sickle cell disease ages 12 and older who have a history of vaso-occlusive events (VOEs).

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