Narrow Label Will Restrict J&J’s Akeega In Prostate Cancer Combination Battle

But Helps Maintain Prostate Cancer Franchise

J&J has only been able to gain approval in BRCA-positive patients in the EU, while AstraZeneca’s rival combination can treat all metastatic prostate cancer patients.

Johnson_and_Johnson

Johnson & Johnson has gained an EU approval for Akeega, a new combination therapy for use in first-line metastatic castration-resistant prostate cancer (mCRPC), but with a label that is more restricted than its key rival, stymieing its commercial prospects.

Akeega is a fixed-dose combination of GSK’s PARP inhibitor Zejula (niraparib) and J&J’s prostate cancer treatment Zytiga (abiraterone acetate),...

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