AbbVie Gets Humira Erosion Right, But Skyrizi/Rinvoq Disappoint Investors

Humira’s US revenue declines by 26% as biosimilar adalimumab makes its debut. Follow-ons Skyrizi and Rinvoq post strong growth, but fall short of Street consensus estimates.

Sales decline
Humira suffered significant biosimilar erosion during Q1, but it was in line with projections • Source: Shutterstock

AbbVie Inc. reported that US sales erosion of top-seller Humira (adalimumab) due to domestic biosimilar competition is proceeding very close to expectations on 27 April, but analysts focused on Humira successors Rinvoq and Skyrizi posting quarterly sales numbers below consensus, although year-over-year growth remained strong.

On its first quarter sales and earnings call, AbbVie noted that Humira – now facing competition from Amgen, Inc.’s Amjevita, with multiple biosimilar versions of adalimumab set to launch later this year – saw a 26.1% year-over-year domestic sales decline during the quarter, still bringing in nearly $2.95bn

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