Lilly Looks For Japan Rebound After Hit From LOEs

Although Lilly Japan's 2022 sales declined 13% on the losses of exclusivity for two important products, the subsidiary has high hopes for three new drugs and other indication expansions. Its first-ever decentralized clinical trial involving Japanese patients, for Alzheimer's candidate donanemab, also turned out successfully.

Lilly sees the Japanese market as the largest market for the firm outside the US
Lilly sees the Japanese market as the largest market for the firm outside the US • Source: Shutterstock

Eli Lilly and Company's Japanese subsidiary saw its sales fall by 13% to JPY216.7bn ($1.57bn) in calendar 2022, hit by the impact of two major local patent expirations and generic competition for its antidepressant Cymbalta (duloxetine) and Alimta (pemetrexed) for non-small cell lung cancer.

Country president Simone Thomsen told a media conference in Tokyo the impact was “not unexpected” and pointed to two new product launches plus four expansions of indications bringing hope for a performance recovery this year

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