First Phase III IBD Trial Reads Out Positive For Janssen’s Tremfya

Data From More Studies Expected Later This Year

The IL-23 inhibitor, entering an increasingly competitive space, posted significant results at Digestive Disease Week from the Phase IIb/III QUASAR induction study in ulcerative colitis.

Ulcerative colitis on clipboard with stethoscope
Two more readouts in UC are expected later this year • Source: Shutterstock

The Janssen Pharmaceutical Cos. of Johnson & Johnson reported positive results from the first of its pivotal trials for Tremfya (guselkumab) in inflammatory bowel disease (IBD) at Digestive Disease Week (DDW) on 9 May, setting the interleukin-23 inhibitor on pace to compete with the two frontrunners in the drug class in the treatment of ulcerative colitis (UC).

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