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Sanofi’s Dupixent Has Greater Benefit In COPD Patients With Higher Type II Inflammation

Full Pivotal Data Suggests

 
• By Ayisha Sharma

The IL-4/IL-3 inhibitor attained a greater reduction in exacerbations in patients with a higher level of a biomarker for type 2 inflammation according to complete pivotal data, but questions remain on the timing of regulatory filings.  

Man in polluted city holding a face mask over his face
Air Pollution Is One Of The Causes of COPD • Source: Shutterstock

Sanofi and Regeneron Pharmaceuticals, Inc.’s inflammatory disease blockbuster Dupixent has shown enhanced efficacy in a subgroup of chronic obstructive pulmonary disease (COPD) patients according to full data from the closely-watched Phase III BOREAS trial, but observers are more concerned with timelines for regulatory filings.

Last year, revenues of the IL-4/IL-3 inhibitor Dupixent (dupilumab), which is approved in a range of inflammatory-driven conditions including atopic...

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• By Anju Ghangurde

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