Lilly Wows ADA Crowd With Obesity Data Across Three-Drug Incretin Portfolio

Weight Loss Of Up To 24.2% With ‘Triple G’ Retatrutide

Lilly may gain its first US approval in obesity with Mounjaro before the end of 2023, but presented data at ADA for it and two other drugs – retatrutide and orforglipron – that also yielded significant weight loss.

Black and white scale on wood floor
Lilly presented data at ADA on three obesity drugs • Source: Shutterstock

Eli Lilly and Company is a few years behind Novo Nordisk A/S in bringing a GLP-1 agonist to market for obesity, but it presented data at the American Diabetes Association (ADA) annual meeting that could give the company a best-in-class portfolio of medicines, including its GLP-1/GIP/glucagon receptor (GGG) triagonist retatrutide, which generated weight loss of up to 24.2% in overweight and obese patients without diabetes at 48 weeks in a Phase II clinical trial presented on 26 June.

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