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Several Options Remain For Cidara’s Flu Candidate After J&J Halts Development

 
• By Ayisha Sharma

Clinical work on the US biotech’s drug-Fc conjugate, CD388, has been stopped by partner Janssen amid a broader company shift, but there are several paths forward for Cidara after the asset showed early promise in a Phase IIa trial.  

hands holding up a paper cut-out showing arrows in different directions
Janssen Could Out-License The Asset Or Return It To Cidara • Source: Shutterstock
Key Takeaways:

  • Janssen has hit pause on mots of its infectious disease programs amidst a strategic change.

  • CD388 has shown early promise in preventing influenza in an ongoing Phase IIa trial.

  • The asset is likely to be developed further by another pharma company or Cidara itself.

Janssen Pharmaceuticals Inc. has hit the brakes on the development of partner Cidara Therapeutics, Inc.’s drug-Fc conjugate (DFC), CD388, for the prevention of influenza, but analysts believe the...

The discontinuation is part of Janssen’s shift away from infectious diseases R&D amid a broader restructuring of its business and does not seem related to CD388’s clinical performance or potential....

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