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Bavarian Drops RSV Program After Phase III Flop

Shifts Focus To Chikungunya

 
• By Ayisha Sharma

The Danish firm’s respiratory syncytial vaccine disappointed in a Phase III trial, marking an unexpected setback after a year of mpox-related successes, prompting all eyes to turn towards a recently-acquired chikungunya vaccine program.  

neon red exit sign against sunset sky
Bavarian Is Leaving The RSV Space After An Unexpected Disappointment • Source: Shutterstock
Key Takeaways:

  • MVA-N RSV showed some efficacy but missed significance in the co-primary endpoint.

Bavarian Nordic A/S’s respiratory syncytial virus (RSV) vaccine candidate, MVA-BN RSV, has missed the mark in the Phase III VANIR trial in older adults, but the firm is confident it can meet its financial guidance with the help of a strong mpox franchise and promising late-stage candidates.

VANIR randomized more than 20,000 people aged 60 or older to a single dose of MVA-BN RSV or placebo, measuring...

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