Pfizer Touts Elrexfio’s Potential For Community Oncology Use In Myeloma

The number of BCMA-directed therapies for treating multiple myeloma grew as the US Food and Drug Administration gave accelerated approval to Elrexfio (elranatamab-bcmm), Pfizer Inc.’s anti-BCMAxCD3 bispecific antibody. Given its flat dosing, dosing schedule and adverse event profile, the company sees the potential for the drug to gain traction in the community oncology setting rather than staying relegated to academic cancer centers, as BCMA-directed therapies have generally been to date.

The FDA gave the green light to Elrexfio on 14 August for patients who have received at least four prior lines of therapy that include a proteasome inhibitor, an immunomodulatory...