Roche’s Divarasib Shows Competitive Data As Monotherapy In KRAS

A Phase I study showed better response and survival rates than Amgen’s Lumakras and Mirati’s Krazati, but investigators said confirmation from larger trials is needed.

KRAS G12C protein
Roche is working to compete with Amgen, Mirati in KRAS inhibition • Source: Shutterstock

Roche Holding AG may have a challenger to approved KRAS G12C inhibitors after reporting data from a Phase I monotherapy study of divarasib (GDC-6036), which investigators reported in the New England Journal of Medicine showed better response and progression-free survival results in patients with advanced solid tumors, including non-small cell lung cancer and colorectal cancer.

Read the full article – start your free trial today!

Join thousands of industry professionals who rely on Scrip for daily insights

  • Start your 7-day free trial
  • Explore trusted news, analysis, and insights
  • Access comprehensive global coverage
  • Enjoy instant access – no credit card required

More from Clinical Trials

More from R&D